Introduction
We aspire to set up a “PAN PROSTATE CANCER GROUP” to harmonise and interrogate Whole Genome DNA Sequence data generated around the world from over 2000 men with prostate cancer, with associated transcriptome and methylome data to include men from different clinical categories, and ethnicities.
This project is about providing breakthrough advances through analysis of a very large series of Whole Genome DNA data from prostate cancer contributed by many of the leading scientists and clinicians working in prostate cancer genomics.
Members
The members of this project contain many of the groups around the world that have generated Whole Genome DNA Sequence (WGS) data using tissue from prostate cancer patients.
Structure
The structure is modelled on other successful consortia such as the PRACTICAL germline consortium as well as the PCAWG consortium. There is a steering committee (SC) composed of the PIs of all groups. There are 3 subcommittees (working groups, WGs) which report to the steering committee (Technical, Clinical and Pathology).
Papers
Key papers have already been published from the participating groups including papers in Nature, Lancet Oncology, Science, Elife and Nature Genetics. Many other publications have been submitted or are in preparation.
Data Access
Sequencing and clinical data is available from the European Genome-phenome Archive and by application to the PPCG consortium. Please complete this concept form and send to ppcg@icr.ac.uk.
Find Out MoreContact Us
PanProstate Cancer Groupc/o Ros Eeles
The Institute of Cancer Research
15 Cotswold Road, Sutton, SM2 5NG, UK.
P: +44 (0) 20 8722 4094
E: ppcg@icr.ac.uk Ros.Eeles@icr.ac.uk